This is a broad–ranging review of the current research on Alzheimer′s disease and other dementias from both basic neuroscience and clinical perspectives. It provides scientists and medical professionals with an extensive introduction and an up–to–date review of cutting–edge scientific advances.This reference begins with an introduction to and overview of the major dementias including Alzheimer′s Disease, Dementia with Lewy Bodies, Frontotemporal Dementia, and Vascular Dementia and explores pathology, manifestations, treatment, and other necessary background information. The second section explores the state–of–the–art research on specific disease mechanisms relevant to dementia such as neuropathology and epidemiology, and genetic risk factors. The third section examines the most recent research on major topics in cognitive and behavioral neuroscience as it relates to dementia, and the final section explores the latest research in neuroimaging.No other reference encompasses the range of topics presented, or combines basic molecular perspectives and cognitive neurosciences. It is an essential tool for physicians and medical students, psychologists, scientists, and allied health professionals including nurses, social workers, and therapists.Biographie de l'auteurDr. Neil W. Kowall is Chief of Neurology and Director of the New England GRECC at the VA Boston Healthcare System; he is also Director of the NIH–funded Boston University Alzheimer′s Disease Center, Professor of Neurology and Pathology at Boston University School of Medicine, and Lecturer in Neurology at Harvard Medical School. He has published over 170 papers in peer–reviewed journals including Science, Nature, the Journal of Neuroscience, and the Annals of Neurology.Dr. Andrew E. Budson is the Deputy Chief of Staff and a member of the Geriatric Research Education Clinical Center (GRECC) at the VA Boston Healthcare System. He is also Associate Director for Research at the Boston University Alzheimer′s Disease Center, Professor of Neurology at Boston University School of Medicine, and Lecturer in Neurology at Harvard Medical School. He was awarded the 2008 Norman Geschwind Prize in Behavioral Neurology and the 2009 Research Award in Geriatric Neurology, both from the American Academy of Neurology, and has published over 75 papers in peer–reviewed journals including the New England Journal of Medicine, Brain, and Cortex.